Rob Allen posted an entry in his blog about using Zend Framework in an IIS on WIndows 2003 Server.
Some of our Zend Framework applications have to run on IIS without ISAPI_Rewrite installed. In these cases we need urls of the form http://www.example.com/index.php?module=mod&controller=con&action=act. I couldn’t get this to work out of the box with Zend Framework 1.5, so wrote my own router called App_Controller_Router_Route_RequestVars.
This code obviously only supports what I needed and I’ve only tested it on IIS for Windows 2003 Server, so you may need to tweak to make it do what you want! Feel free to share any fixes